Correlation between 5-fluorouracil metabolism and treatment response in two variants of C26 murine colon carcinoma

Following an i.p. dose of 150 mg kg(−1) 5-fluorouracil (5-FU), drug uptake and metabolism over a 2-h period were studied by in vivo (19)F magnetic resonance spectroscopy (MRS) for the murine colon carcinoma lines C26-B (5-FU-insensitive; n=11) and C26-10 (5-FU-sensitive; n=15) implanted s.c. in Balb...

Descripción completa

Detalles Bibliográficos
Autores principales: Kamm, Y J L, Peters, G J, Hull, W E, Punt, C J A, Heerschap, A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2003
Materias:
Experimental Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2376920/
https://www.ncbi.nlm.nih.gov/pubmed/12915890
http://dx.doi.org/10.1038/sj.bjc.6601162

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2376920/
https://www.ncbi.nlm.nih.gov/pubmed/12915890
http://dx.doi.org/10.1038/sj.bjc.6601162

Ejemplares similares