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Cytotoxic T-cell precursor frequencies to HER-2 (369 – 377) in patients with HER-2/neu-positive epithelial tumours

HER-2/neu oncoprotein contains several major histocompatibility complex class I-restricted epitopes, which are recognised by cytotoxic T lymphocyte (CTL) on autologous tumours and therefore can be used in immune-based cancer therapies. Of these, the most extensively studied is HER-2(9(369)). In the...

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Detalles Bibliográficos
Autores principales: Sotiropoulou, P A, Perez, S A, Iliopoulou, E G, Missitzis, I, Voelter, V, Echner, H, Baxevanis, C N, Papamichail, M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2376937/
https://www.ncbi.nlm.nih.gov/pubmed/12966425
http://dx.doi.org/10.1038/sj.bjc.6601244