A mechanism of resistance to TRAIL/Apo2L-induced apoptosis of newly established glioma cell line and sensitisation to TRAIL by genotoxic agents

Most tumour cells are sensitive to TRAIL-induced apoptosis, but not normal cells; thus, cancer therapy using TRAIL is expected clinically. Several tumour cells are resistant to TRAIL-induced apoptosis, and various mechanisms of such resistance were reported in individual cases. In this study, we est...

Descripción completa

Detalles Bibliográficos
Autores principales: Arizono, Y, Yoshikawa, H, Naganuma, H, Hamada, Y, Nakajima, Y, Tasaka, K
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2003
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377044/
https://www.ncbi.nlm.nih.gov/pubmed/12610517
http://dx.doi.org/10.1038/sj.bjc.6600666

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377044/
https://www.ncbi.nlm.nih.gov/pubmed/12610517
http://dx.doi.org/10.1038/sj.bjc.6600666

Ejemplares similares