Cargando…

A mechanism of resistance to TRAIL/Apo2L-induced apoptosis of newly established glioma cell line and sensitisation to TRAIL by genotoxic agents

Most tumour cells are sensitive to TRAIL-induced apoptosis, but not normal cells; thus, cancer therapy using TRAIL is expected clinically. Several tumour cells are resistant to TRAIL-induced apoptosis, and various mechanisms of such resistance were reported in individual cases. In this study, we est...

Descripción completa

Detalles Bibliográficos
Autores principales:	Arizono, Y, Yoshikawa, H, Naganuma, H, Hamada, Y, Nakajima, Y, Tasaka, K
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2003
Materias:	Genetics and Genomics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377044/ https://www.ncbi.nlm.nih.gov/pubmed/12610517 http://dx.doi.org/10.1038/sj.bjc.6600666

Ejemplares similares

TRAIL-β and TRAIL-γ: two novel splice variants of the human TNF-related apoptosis-inducing ligand (TRAIL) without apoptotic potential
por: Krieg, A, et al.
Publicado: (2003)

Functional screening of genes suppressing TRAIL-induced apoptosis: distinct inhibitory activities of Bcl-X(L) and Bcl-2
por: Kim, I-K, et al.
Publicado: (2003)

Nutlin-3 preferentially sensitises wild-type p53-expressing cancer cells to DR5-selective TRAIL over rhTRAIL
por: Meijer, A, et al.
Publicado: (2013)

Irradiation specifically sensitises solid tumour cell lines to TRAIL mediated apoptosis
por: Marini, Patrizia, et al.
Publicado: (2005)

Mesenchymal Stem Cell Expressing TRAIL as Targeted Therapy against Sensitised Tumour
por: Shaik Fakiruddin, Kamal, et al.
Publicado: (2018)

Bortezomib sensitises TRAIL-resistant HPV-positive head and neck cancer cells to TRAIL through a caspase-dependent, E6-independent mechanism
por: Bullenkamp, J, et al.
Publicado: (2014)

Activation of the aryl hydrocarbon receptor sensitises human keratinocytes for CD95L- and TRAIL-induced apoptosis
por: Stolpmann, K, et al.
Publicado: (2012)

Trailing TRAIL Resistance: Novel Targets for TRAIL Sensitization in Cancer Cells
por: Trivedi, Rachana, et al.
Publicado: (2015)

On the Trail of Agent Orange
por: Tenenbaum, DJ
Publicado: (2003)

Mechanism of genotoxicity induced by targeted cytoplasmic irradiation
por: Hong, M, et al.
Publicado: (2010)

TRAIL Deficiency Contributes to Diabetic Nephropathy in Fat-Fed ApoE(-/-) Mice
por: Cartland, Siân P., et al.
Publicado: (2014)

TRAIL sensitisation by arsenic trioxide is caspase-8 dependent and involves modulation of death receptor components and Akt
por: Szegezdi, E, et al.
Publicado: (2006)

Differential gene expression profiles of gastric cancer cells established from primary tumour and malignant ascites
por: Sakakura, C, et al.
Publicado: (2002)

Sorafenib Sensitizes Solid Tumors to Apo2L/TRAIL and Apo2L/TRAIL Receptor Agonist Antibodies by the Jak2-Stat3-Mcl1 Axis
por: Abdulghani, Junaid, et al.
Publicado: (2013)

Efficacy of adenovirally expressed soluble TRAIL in human glioma organotypic slice culture and glioma xenografts
por: Liu, Y, et al.
Publicado: (2011)

α-Tocopheryl succinate sensitises a T lymphoma cell line to TRAIL-induced apoptosis by suppressing NF-κB activation
por: Dalen, H, et al.
Publicado: (2003)

TRAIL/TRAIL Receptor System and Susceptibility to Multiple Sclerosis
por: López-Gómez, Carlos, et al.
Publicado: (2011)

TRAIL combinations: The new ‘trail’ for cancer therapy (Review)
por: REFAAT, ALAA, et al.
Publicado: (2014)

Hot on the Trail of TRP Channel Structure
por: Moiseenkova-Bell, Vera Y., et al.
Publicado: (2009)

Co-transduction of Apaf-1 and caspase-9 highly enhances p53-mediated apoptosis in gliomas
por: Shinoura, N, et al.
Publicado: (2002)

N-glycosylation of mouse TRAIL-R and human TRAIL-R1 enhances TRAIL-induced death
por: Dufour, Florent, et al.
Publicado: (2017)

Psychometric Properties of the Trail Walking Test for People With Stroke
por: Ng, Shamay S. M., et al.
Publicado: (2022)

Crossed TRAILs
por: Wells, William A.
Publicado: (2002)

The white trail /
por: Dafydd, Fflur
Publicado: (2011)

The information trail
por: Berman, Carol
Publicado: (2016)

John Trail
Publicado: (1889)

Drug-induced caspase 8 upregulation sensitises cisplatin-resistant ovarian carcinoma cells to rhTRAIL-induced apoptosis
por: Duiker, E W, et al.
Publicado: (2011)

Possible Novel Therapy for Malignant Gliomas with Secretable Trimeric TRAIL
por: Jeong, Moonsup, et al.
Publicado: (2009)

Tumor-targeted delivery of biologically active TRAIL protein
por: Zhang, H-Y, et al.
Publicado: (2010)

Caspase-8 activation by TRAIL monotherapy predicts responses to IAPi and TRAIL combination treatment in breast cancer cell lines
por: Polanski, R, et al.
Publicado: (2015)

The regulation of combined treatment-induced cell death with recombinant TRAIL and bortezomib through TRAIL signaling in TRAIL-resistant cells
por: Ryu, Sunhyo, et al.
Publicado: (2018)

TRAIL-R1 and TRAIL-R2 Mediate TRAIL-Dependent Apoptosis in Activated Primary Human B Lymphocytes
por: Staniek, Julian, et al.
Publicado: (2019)

TERT promoter mutations in gliomas, genetic associations and clinico-pathological correlations
por: Labussière, M, et al.
Publicado: (2014)

In vitro sensitivity testing of minimally passaged and uncultured gliomas with TRAIL and/or chemotherapy drugs
por: Ashley, D M, et al.
Publicado: (2008)

In vitro sensitivity testing of minimally passaged and uncultured gliomas with TRAIL and/or chemotherapy drugs
por: Ashley, D M, et al.
Publicado: (2009)

N-glycosylation of mouse TRAIL-R restrains TRAIL-induced apoptosis
por: Estornes, Yann, et al.
Publicado: (2018)

TRAIL Induces Nuclear Translocation and Chromatin Localization of TRAIL Death Receptors
por: Mert, Ufuk, et al.
Publicado: (2019)

Specific Incremental Test for Aerobic Fitness in Trail Running: IncremenTrail
por: Doucende, Grégory, et al.
Publicado: (2022)

Newly established tumourigenic primary human colon cancer cell lines are sensitive to TRAIL-induced apoptosis in vitro and in vivo
por: Oikonomou, E, et al.
Publicado: (2007)

Newly established tumourigenic primary human colon cancer cell lines are sensitive to TRAIL induced apoptosis in vitro and in vivo
por: Oikonomou, E, et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_hc9tj9namqskr9r7igs4oqub3k