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Effector CD8(+)CD45RO(−)CD27(−)T cells have signalling defects in patients with squamous cell carcinoma of the head and neck

A subset of circulating T cells (CD8(+)CD45RO(−)CD27(−)) with a naïve phenotype, but mediating effector function, is considered to play an important role in host antitumour defence. To investigate the attributes of these effector T cells in patients with squamous cell carcinoma (SCC) of the head and...

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Detalles Bibliográficos
Autores principales: Kuss, I, Donnenberg, A D, Gooding, W, Whiteside, T L
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377049/
https://www.ncbi.nlm.nih.gov/pubmed/12610507
http://dx.doi.org/10.1038/sj.bjc.6600694