Functional screening of genes suppressing TRAIL-induced apoptosis: distinct inhibitory activities of Bcl-X(L) and Bcl-2

TNF-related apoptosis-inducing ligand (TRAIL) is known to selectively induce apoptosis in various tumour cells. However, downstream-signalling of TRAIL-receptor is not well defined. A functional genetic screening was performed to isolate genes interfering with TRAIL-induced apoptosis using cDNA retr...

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Detalles Bibliográficos
Autores principales: Kim, I-K, Jung, Y-K, Noh, D-Y, Song, Y-S, Choi, C-H, Oh, B-H, Masuda, E S
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2003
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377084/
https://www.ncbi.nlm.nih.gov/pubmed/12644829
http://dx.doi.org/10.1038/sj.bjc.6600795

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377084/
https://www.ncbi.nlm.nih.gov/pubmed/12644829
http://dx.doi.org/10.1038/sj.bjc.6600795

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