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Unc45b Forms a Cytosolic Complex with Hsp90 and Targets the Unfolded Myosin Motor Domain

Myosin folding and assembly in striated muscle is mediated by the general chaperones Hsc70 and Hsp90 and a myosin specific co-chaperone, UNC45. Two UNC45 genes are found in vertebrates, including a striated muscle specific form, Unc45b. We have investigated the role of Unc45b in myosin folding. Epit...

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Detalles Bibliográficos
Autores principales: Srikakulam, Rajani, Liu, Li, Winkelmann, Donald A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377097/
https://www.ncbi.nlm.nih.gov/pubmed/18478096
http://dx.doi.org/10.1371/journal.pone.0002137