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New insights into the actions of bisphosphonate zoledronic acid in breast cancer cells by dual RhoA-dependent and -independent effects

Zoledronic acid (ZOL) is a nitrogen-containing bisphosphonate and its use in reducing osteoporosis and cancer-induced osteolysis is increasing. Recent findings indicated that ZOL has a direct effect on cancer cells. In this study, the effect of ZOL was examined on the aggressive MDA-MB-231 breast ca...

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Detalles Bibliográficos
Autores principales: Denoyelle, C, Hong, L, Vannier, J-P, Soria, J, Soria, C
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377117/
https://www.ncbi.nlm.nih.gov/pubmed/12771933
http://dx.doi.org/10.1038/sj.bjc.6600925