Quinazoline-based α1-adrenoceptor antagonists induce prostate cancer cell apoptosis via TGF-β signalling and IκBα induction

Previous studies documented the ability of quinazoline-based α1-adrenoceptor antagonists to induce apoptosis in prostate cancer cells via an α1-adrenoceptor-independent mechanism. In this study we investigated the molecular events initiating this apoptotic effect. Since transforming growth factor-β1...

Descripción completa

Detalles Bibliográficos
Autores principales: Partin, J V, Anglin, I E, Kyprianou, N
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2003
Materias:
Experimental Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377124/
https://www.ncbi.nlm.nih.gov/pubmed/12771931
http://dx.doi.org/10.1038/sj.bjc.6600961

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377124/
https://www.ncbi.nlm.nih.gov/pubmed/12771931
http://dx.doi.org/10.1038/sj.bjc.6600961

Ejemplares similares