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Quinazoline-based α1-adrenoceptor antagonists induce prostate cancer cell apoptosis via TGF-β signalling and IκBα induction

Previous studies documented the ability of quinazoline-based α1-adrenoceptor antagonists to induce apoptosis in prostate cancer cells via an α1-adrenoceptor-independent mechanism. In this study we investigated the molecular events initiating this apoptotic effect. Since transforming growth factor-β1...

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Detalles Bibliográficos
Autores principales:	Partin, J V, Anglin, I E, Kyprianou, N
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2003
Materias:	Experimental Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377124/ https://www.ncbi.nlm.nih.gov/pubmed/12771931 http://dx.doi.org/10.1038/sj.bjc.6600961

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