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In vivo evolution of tumour cells after the generation of double-strand DNA breaks

In vitro, the ratio of single- to double-strand DNA breaks (DSB) and their absolute values determine the cell death pathway. The consequences of the generation of various numbers of DSB generated in vivo in tumour cells have been analysed in two different experimental tumour models. Synchronisation...

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Detalles Bibliográficos
Autores principales: Mekid, H, Tounekti, O, Spatz, A, Cemazar, M, El Kebir, F Z, Mir, L M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377151/
https://www.ncbi.nlm.nih.gov/pubmed/12771993
http://dx.doi.org/10.1038/sj.bjc.6600959