Inhibition of IL-6+IL-6 soluble receptor-stimulated aromatase activity by the IL-6 antagonist, Sant 7, in breast tissue-derived fibroblasts

Interleukin 6 (IL-6) and its soluble receptor (IL-6sR) can markedly stimulate aromatase activity in cultured fibroblasts derived from normal or malignant breast tissues. IL-6 acts by binding to a low-affinity membrane-spanning receptor (IL-6R), which must associate with a high-affinity receptor (gp1...

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Detalles Bibliográficos
Autores principales: Purohit, A, Singh, A, Ghilchik, M W, Serlupi-Crescenzi, O, Reed, M J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2003
Materias:
Experimental Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377164/
https://www.ncbi.nlm.nih.gov/pubmed/12592380
http://dx.doi.org/10.1038/sj.bjc.6600785

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377164/
https://www.ncbi.nlm.nih.gov/pubmed/12592380
http://dx.doi.org/10.1038/sj.bjc.6600785

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