Association between telomere length and V(H) gene mutation status in chronic lymphocytic leukaemia: clinical and biological implications

The immunoglobulin V(H) gene mutation status can divide B-cell chronic lymphocytic leukaemia (CLL) into two entities with a different clinical course. Cases with unmutated V(H) genes, considered to evolve from pregerminal centre (GC) cells, have a worse outcome compared to cases showing mutated V(H)...

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Detalles Bibliográficos
Autores principales: Hultdin, M, Rosenquist, R, Thunberg, U, Tobin, G, Norrback, K-F, Johnson, A, Sundström, C, Roos, G
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2003
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377180/
https://www.ncbi.nlm.nih.gov/pubmed/12592375
http://dx.doi.org/10.1038/sj.bjc.6600763

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377180/
https://www.ncbi.nlm.nih.gov/pubmed/12592375
http://dx.doi.org/10.1038/sj.bjc.6600763

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