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Association between telomere length and V(H) gene mutation status in chronic lymphocytic leukaemia: clinical and biological implications
The immunoglobulin V(H) gene mutation status can divide B-cell chronic lymphocytic leukaemia (CLL) into two entities with a different clinical course. Cases with unmutated V(H) genes, considered to evolve from pregerminal centre (GC) cells, have a worse outcome compared to cases showing mutated V(H)...
Autores principales: | Hultdin, M, Rosenquist, R, Thunberg, U, Tobin, G, Norrback, K-F, Johnson, A, Sundström, C, Roos, G |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377180/ https://www.ncbi.nlm.nih.gov/pubmed/12592375 http://dx.doi.org/10.1038/sj.bjc.6600763 |
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