An ultrasensitive sorting mechanism for EGF Receptor Endocytosis

BACKGROUND: The Epidermal Growth Factor (EGF) receptor has been shown to internalize via clathrin-independent endocytosis (CIE) in a ligand concentration dependent manner. From a modeling point of view, this resembles an ultrasensitive response, which is the ability of signaling networks to suppress...

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Detalles Bibliográficos
Autores principales: Schmidt-Glenewinkel, Hannah, Vacheva, Ivayla, Hoeller, Daniela, Dikic, Ivan, Eils, Roland
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377235/
https://www.ncbi.nlm.nih.gov/pubmed/18394191
http://dx.doi.org/10.1186/1752-0509-2-32

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377235/
https://www.ncbi.nlm.nih.gov/pubmed/18394191
http://dx.doi.org/10.1186/1752-0509-2-32

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