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An ultrasensitive sorting mechanism for EGF Receptor Endocytosis

BACKGROUND: The Epidermal Growth Factor (EGF) receptor has been shown to internalize via clathrin-independent endocytosis (CIE) in a ligand concentration dependent manner. From a modeling point of view, this resembles an ultrasensitive response, which is the ability of signaling networks to suppress...

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Detalles Bibliográficos
Autores principales:	Schmidt-Glenewinkel, Hannah, Vacheva, Ivayla, Hoeller, Daniela, Dikic, Ivan, Eils, Roland
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377235/ https://www.ncbi.nlm.nih.gov/pubmed/18394191 http://dx.doi.org/10.1186/1752-0509-2-32

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