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Effects of long-term low-dose oxygen supplementation on the epithelial function, collagen metabolism and interstitial fibrogenesis in the guinea pig lung

BACKGROUND: The patient population receiving long-term oxygen therapy has increased with the rising morbidity of COPD. Although high-dose oxygen induces pulmonary edema and interstitial fibrosis, potential lung injury caused by long-term exposure to low-dose oxygen has not been fully analyzed. This...

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Detalles Bibliográficos
Autores principales: Aoki, Takuya, Yamasawa, Fumihiro, Kawashiro, Takeo, Shibata, Tetsuichi, Ishizaka, Akitoshi, Urano, Tetsuya, Okada, Yasumasa
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377243/
https://www.ncbi.nlm.nih.gov/pubmed/18439301
http://dx.doi.org/10.1186/1465-9921-9-37