A stable explant culture of HER2/neu invasive carcinoma supported by alpha-Smooth Muscle Actin expressing stromal cells to evaluate therapeutic agents

BACKGROUND: To gain a better understanding of the effects of therapeutic agents on the tumor microenvironment in invasive cancers, we developed a co-culture model from an invasive lobular carcinoma. Tumor cells expressing HER2/neu organize in nests surrounded by alpha-Smooth Muscle Actin (α-SMA) exp...

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Detalles Bibliográficos
Autor principal: Piechocki, Marie P
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377275/
https://www.ncbi.nlm.nih.gov/pubmed/18435859
http://dx.doi.org/10.1186/1471-2407-8-119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377275/
https://www.ncbi.nlm.nih.gov/pubmed/18435859
http://dx.doi.org/10.1186/1471-2407-8-119

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