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Endogenous ATP release inhibits electrogenic Na(+) absorption and stimulates Cl(−) secretion in MDCK cells

Our previous studies with a line of Madin-Darby canine kidney (MDCK) cells (FL-MDCK) transfected with FLAG-labeled α, β, and γ subunits of epithelial Na(+) channel (ENaC) showed that, although most of the short-circuit current (I(sc)) was amiloride sensitive (AS-I(sc)), there was also an amiloride-i...

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Detalles Bibliográficos
Autores principales: Xie, Yi, Schafer, James A.
Formato: Texto
Lenguaje:English
Publicado: Springer Netherlands 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377323/
https://www.ncbi.nlm.nih.gov/pubmed/18368527
http://dx.doi.org/10.1007/s11302-007-9053-3