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dSETDB1 and SU(VAR)3–9 Sequentially Function during Germline-Stem Cell Differentiation in Drosophila melanogaster

Germline-stem cells (GSCs) produce gametes and are thus true “immortal stem cells”. In Drosophila ovaries, GSCs divide asymmetrically to produce daughter GSCs and cystoblasts, and the latter differentiate into germline cysts. Here we show that the histone-lysine methyltransferase dSETDB1, located in...

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Detalles Bibliográficos
Autores principales: Yoon, Jeongheon, Lee, Kyu-Sun, Park, Jung Sun, Yu, Kweon, Paik, Sang-Gi, Kang, Yong-Kook
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377335/
https://www.ncbi.nlm.nih.gov/pubmed/18493619
http://dx.doi.org/10.1371/journal.pone.0002234