Pharmacological Inhibition of Nicotinamide Phosphoribosyltransferase/Visfatin Enzymatic Activity Identifies a New Inflammatory Pathway Linked to NAD

Nicotinamide phosphoribosyltransferase (NAMPT), also known as visfatin, is the rate-limiting enzyme in the salvage pathway of NAD biosynthesis from nicotinamide. Since its expression is upregulated during inflammation, NAMPT represents a novel clinical biomarker in acute lung injury, rheumatoid arth...

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Detalles Bibliográficos
Autores principales: Busso, Nathalie, Karababa, Mahir, Nobile, Massimo, Rolaz, Aline, Van Gool, Frédéric, Galli, Mara, Leo, Oberdan, So, Alexander, De Smedt, Thibaut
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377336/
https://www.ncbi.nlm.nih.gov/pubmed/18493620
http://dx.doi.org/10.1371/journal.pone.0002267

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377336/
https://www.ncbi.nlm.nih.gov/pubmed/18493620
http://dx.doi.org/10.1371/journal.pone.0002267

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