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Th1 Disabled Function in Response to TLR4 Stimulation of Monocyte-Derived DC from Patients Chronically-Infected by Hepatitis C Virus

BACKGROUND: Lack of protective antibodies and inefficient cytotoxic responses are characteristics of chronic hepatitis C infection. A defect in dendritic cell (DC) function has thus been suspected, but this remains a controversial issue. METHODS AND FINDINGS: Here we show that monocyte-derived DC (M...

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Detalles Bibliográficos
Autores principales: Perrin-Cocon, Laure, Agaugué, Sophie, Diaz, Olivier, Vanbervliet, Béatrice, Dollet, Sandra, Guironnet-Paquet, Aurélie, André, Patrice, Lotteau, Vincent
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377338/
https://www.ncbi.nlm.nih.gov/pubmed/18509450
http://dx.doi.org/10.1371/journal.pone.0002260