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Th1 Disabled Function in Response to TLR4 Stimulation of Monocyte-Derived DC from Patients Chronically-Infected by Hepatitis C Virus
BACKGROUND: Lack of protective antibodies and inefficient cytotoxic responses are characteristics of chronic hepatitis C infection. A defect in dendritic cell (DC) function has thus been suspected, but this remains a controversial issue. METHODS AND FINDINGS: Here we show that monocyte-derived DC (M...
Autores principales: | Perrin-Cocon, Laure, Agaugué, Sophie, Diaz, Olivier, Vanbervliet, Béatrice, Dollet, Sandra, Guironnet-Paquet, Aurélie, André, Patrice, Lotteau, Vincent |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377338/ https://www.ncbi.nlm.nih.gov/pubmed/18509450 http://dx.doi.org/10.1371/journal.pone.0002260 |
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