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The bacterial and mitochondrial ribosomal A-site molecular switches possess different conformational substates

The A site of the small ribosomal subunit participates in the fidelity of decoding by switching between two states, a resting ‘off’ state and an active decoding ‘on’ state. Eight crystal structures of RNA duplexes containing two minimal decoding A sites of the Homo sapiens mitochondrial wild-type, t...

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Detalles Bibliográficos
Autores principales: Kondo, Jiro, Westhof, Eric
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377432/
https://www.ncbi.nlm.nih.gov/pubmed/18346970
http://dx.doi.org/10.1093/nar/gkn112