Combined in silico and experimental identification of the Pyrococcus abyssi H/ACA sRNAs and their target sites in ribosomal RNAs

How far do H/ACA sRNPs contribute to rRNA pseudouridylation in Archaea was still an open question. Hence here, by computational search in three Pyrococcus genomes, we identified seven H/ACA sRNAs and predicted their target sites in rRNAs. In parallel, we experimentally identified 17 Ψ residues in P....

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Detalles Bibliográficos
Autores principales: Muller, Sébastien, Leclerc, Fabrice, Behm-Ansmant, Isabelle, Fourmann, Jean-Baptiste, Charpentier, Bruno, Branlant, Christiane
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377435/
https://www.ncbi.nlm.nih.gov/pubmed/18304947
http://dx.doi.org/10.1093/nar/gkn077

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377435/
https://www.ncbi.nlm.nih.gov/pubmed/18304947
http://dx.doi.org/10.1093/nar/gkn077

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