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Combined in silico and experimental identification of the Pyrococcus abyssi H/ACA sRNAs and their target sites in ribosomal RNAs
How far do H/ACA sRNPs contribute to rRNA pseudouridylation in Archaea was still an open question. Hence here, by computational search in three Pyrococcus genomes, we identified seven H/ACA sRNAs and predicted their target sites in rRNAs. In parallel, we experimentally identified 17 Ψ residues in P....
Autores principales: | Muller, Sébastien, Leclerc, Fabrice, Behm-Ansmant, Isabelle, Fourmann, Jean-Baptiste, Charpentier, Bruno, Branlant, Christiane |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377435/ https://www.ncbi.nlm.nih.gov/pubmed/18304947 http://dx.doi.org/10.1093/nar/gkn077 |
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