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Sequence homology and microhomology dominate chromosomal double-strand break repair in African trypanosomes

Genetic diversity in fungi and mammals is generated through mitotic double-strand break-repair (DSBR), typically involving homologous recombination (HR) or non-homologous end joining (NHEJ). Microhomology-mediated joining appears to serve a subsidiary function. The African trypanosome, a divergent p...

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Detalles Bibliográficos
Autores principales: Glover, Lucy, McCulloch, Richard, Horn, David
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377438/
https://www.ncbi.nlm.nih.gov/pubmed/18334531
http://dx.doi.org/10.1093/nar/gkn104