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Sequence homology and microhomology dominate chromosomal double-strand break repair in African trypanosomes
Genetic diversity in fungi and mammals is generated through mitotic double-strand break-repair (DSBR), typically involving homologous recombination (HR) or non-homologous end joining (NHEJ). Microhomology-mediated joining appears to serve a subsidiary function. The African trypanosome, a divergent p...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377438/ https://www.ncbi.nlm.nih.gov/pubmed/18334531 http://dx.doi.org/10.1093/nar/gkn104 |