Cargando…
Sequence homology and microhomology dominate chromosomal double-strand break repair in African trypanosomes
Genetic diversity in fungi and mammals is generated through mitotic double-strand break-repair (DSBR), typically involving homologous recombination (HR) or non-homologous end joining (NHEJ). Microhomology-mediated joining appears to serve a subsidiary function. The African trypanosome, a divergent p...
Autores principales: | Glover, Lucy, McCulloch, Richard, Horn, David |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2008
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377438/ https://www.ncbi.nlm.nih.gov/pubmed/18334531 http://dx.doi.org/10.1093/nar/gkn104 |
Ejemplares similares
-
Microhomology-mediated deletion and gene conversion in African trypanosomes
por: Glover, Lucy, et al.
Publicado: (2011) -
The MRN complex promotes DNA repair by homologous recombination and restrains antigenic variation in African trypanosomes
por: Mehnert, Ann-Kathrin, et al.
Publicado: (2021) -
Antigenic variation in African trypanosomes: the importance of chromosomal and nuclear context in VSG expression control
por: Glover, Lucy, et al.
Publicado: (2013) -
RPA Antagonizes Microhomology-Mediated Repair of DNA Double-Strand Breaks
por: Deng, Sarah K, et al.
Publicado: (2014) -
DNA breaks as triggers for antigenic variation in African trypanosomes
por: Alsford, Sam, et al.
Publicado: (2009)