A new kinetic model reveals the synergistic effect of E-, P- and A-sites on +1 ribosomal frameshifting

Programmed ribosomal frameshifting (PRF) is a process by which ribosomes produce two different polypeptides from the same mRNA. In this study, we propose three different kinetic models of +1 PRF, incorporating the effects of the ribosomal E-, P- and A-sites toward promoting efficient +1 frameshiftin...

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Detalles Bibliográficos
Autores principales: Liao, Pei-Yu, Gupta, Prateek, Petrov, Alexey N., Dinman, Jonathan D., Lee, Kelvin H.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377451/
https://www.ncbi.nlm.nih.gov/pubmed/18344525
http://dx.doi.org/10.1093/nar/gkn100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377451/
https://www.ncbi.nlm.nih.gov/pubmed/18344525
http://dx.doi.org/10.1093/nar/gkn100

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