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A new kinetic model reveals the synergistic effect of E-, P- and A-sites on +1 ribosomal frameshifting
Programmed ribosomal frameshifting (PRF) is a process by which ribosomes produce two different polypeptides from the same mRNA. In this study, we propose three different kinetic models of +1 PRF, incorporating the effects of the ribosomal E-, P- and A-sites toward promoting efficient +1 frameshiftin...
Autores principales: | Liao, Pei-Yu, Gupta, Prateek, Petrov, Alexey N., Dinman, Jonathan D., Lee, Kelvin H. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377451/ https://www.ncbi.nlm.nih.gov/pubmed/18344525 http://dx.doi.org/10.1093/nar/gkn100 |
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