Functional analysis of Leishmania major cyclophilin

A potent immunosuppressive drug cyclosporin A (CsA) is known to inhibit human cell infection by the pathogenic protozoan parasite Leishmania major both in vitro and in vivo. The proposed mechanism of action involves CsA binding to Leishmania major-expressed cyclophilin and subsequent down-regulation...

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Detalles Bibliográficos
Autores principales: Yurchenko, Vyacheslav, Xue, Zhu, Sherry, Barbara, Bukrinsky, Michael
Formato: Texto
Lenguaje:English
Publicado: Australian Society for Parasitology Inc. Published by Elsevier Ltd. 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377454/
https://www.ncbi.nlm.nih.gov/pubmed/17991468
http://dx.doi.org/10.1016/j.ijpara.2007.10.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377454/
https://www.ncbi.nlm.nih.gov/pubmed/17991468
http://dx.doi.org/10.1016/j.ijpara.2007.10.001

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