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Functional analysis of Leishmania major cyclophilin
A potent immunosuppressive drug cyclosporin A (CsA) is known to inhibit human cell infection by the pathogenic protozoan parasite Leishmania major both in vitro and in vivo. The proposed mechanism of action involves CsA binding to Leishmania major-expressed cyclophilin and subsequent down-regulation...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Australian Society for Parasitology Inc. Published by Elsevier Ltd.
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377454/ https://www.ncbi.nlm.nih.gov/pubmed/17991468 http://dx.doi.org/10.1016/j.ijpara.2007.10.001 |