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Using RNase sequence specificity to refine the identification of RNA-protein binding regions

Massively parallel pyrosequencing is a high-throughput technology that can sequence hundreds of thousands of DNA/RNA fragments in a single experiment. Combining it with immunoprecipitation-based biochemical assays, such as cross-linking immunoprecipitation (CLIP), provides a genome-wide method to de...

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Detalles Bibliográficos
Autores principales: Wang, Xin, Wang, Guohua, Shen, Changyu, Li, Lang, Wang, Xinguo, Mooney, Sean D, Edenberg, Howard J, Sanford, Jeremy R, Liu, Yunlong
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2386059/
https://www.ncbi.nlm.nih.gov/pubmed/18366606
http://dx.doi.org/10.1186/1471-2164-9-S1-S17