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Molecular architecture of the kinetochore-microtubule attachment site is conserved between point and regional centromeres

Point and regional centromeres specify a unique site on each chromosome for kinetochore assembly. The point centromere in budding yeast is a unique 150-bp DNA sequence, which supports a kinetochore with only one microtubule attachment. In contrast, regional centromeres are complex in architecture, c...

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Detalles Bibliográficos
Autores principales: Joglekar, Ajit P., Bouck, David, Finley, Ken, Liu, Xingkun, Wan, Yakun, Berman, Judith, He, Xiangwei, Salmon, E.D., Bloom, Kerry S.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2386099/
https://www.ncbi.nlm.nih.gov/pubmed/18474626
http://dx.doi.org/10.1083/jcb.200803027