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Neural RNA-binding protein Musashi1 inhibits translation initiation by competing with eIF4G for PABP

Musashi1 (Msi1) is an RNA-binding protein that is highly expressed in neural stem cells. We previously reported that Msi1 contributes to the maintenance of the immature state and self-renewal activity of neural stem cells through translational repression of m-Numb. However, its translation repressio...

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Detalles Bibliográficos
Autores principales: Kawahara, Hironori, Imai, Takao, Imataka, Hiroaki, Tsujimoto, Masafumi, Matsumoto, Ken, Okano, Hideyuki
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2386104/
https://www.ncbi.nlm.nih.gov/pubmed/18490513
http://dx.doi.org/10.1083/jcb.200708004