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Application of bioinformatics-coupled experimental analysis reveals a new transport-competent nuclear localization signal in the nucleoprotein of Influenza A virus strain

BACKGROUND: Two nuclear localization sequences (NLS) in influenza A virus nucleoprotein (NP) have been demonstrated to be critical for nuclear import of NP and viral ribonucleoprotein complexes. However, a deletion mutant lacking these two signals was still able to localize to the nucleus suggesting...

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Detalles Bibliográficos
Autores principales: Ketha, Krishna Mohan V, Atreya, Chintamani D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2386121/
https://www.ncbi.nlm.nih.gov/pubmed/18442378
http://dx.doi.org/10.1186/1471-2121-9-22