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Activation of Estrogen Receptor-α by E2 or EGF Induces Temporally Distinct Patterns of Large-Scale Chromatin Modification and mRNA Transcription

Estrogen receptor-α (ER) transcription function is regulated in a ligand-dependent (e.g., estradiol, E2) or ligand-independent (e.g., growth factors) manner. Our laboratory seeks to understand these two modes of action. Using a cell line that contains a visible prolactin enhancer/promoter array (PRL...

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Detalles Bibliográficos
Autores principales: Berno, Valeria, Amazit, Larbi, Hinojos, Cruz, Zhong, Jeannie, Mancini, Maureen G., Dave Sharp, Zelton, Mancini, Michael A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2386239/
https://www.ncbi.nlm.nih.gov/pubmed/18509470
http://dx.doi.org/10.1371/journal.pone.0002286