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A Constitutional Translocation t(1;17)(p36.2;q11.2) in a Neuroblastoma Patient Disrupts the Human NBPF1 and ACCN1 Genes

The human 1p36 region is deleted in many different types of tumors, and so it probably harbors one or more tumor suppressor genes. In a Belgian neuroblastoma patient, a constitutional balanced translocation t(1;17)(p36.2;q11.2) may have led to the development of the tumor by disrupting or activating...

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Detalles Bibliográficos
Autores principales: Vandepoele, Karl, Andries, Vanessa, Van Roy, Nadine, Staes, Katrien, Vandesompele, Jo, Laureys, Geneviève, De Smet, Els, Berx, Geert, Speleman, Frank, van Roy, Frans
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2386287/
https://www.ncbi.nlm.nih.gov/pubmed/18493581
http://dx.doi.org/10.1371/journal.pone.0002207