Kinetics and Ligand-Binding Preferences of Mycobacterium tuberculosis Thymidylate Synthases, ThyA and ThyX

BACKGROUND: Mycobacterium tuberculosis kills approximately 2 million people each year and presents an urgent need to identify new targets and new antitubercular drugs. Thymidylate synthase (TS) enzymes from other species offer good targets for drug development and the M. tuberculosis genome contains...

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Detalles Bibliográficos
Autores principales: Hunter, Joshua H., Gujjar, Ramesh, Pang, Cullen K. T., Rathod, Pradipsinh K.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2386288/
https://www.ncbi.nlm.nih.gov/pubmed/18493582
http://dx.doi.org/10.1371/journal.pone.0002237

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2386288/
https://www.ncbi.nlm.nih.gov/pubmed/18493582
http://dx.doi.org/10.1371/journal.pone.0002237

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