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A systems biology approach to analyse amplification in the JAK2-STAT5 signalling pathway

BACKGROUND: The amplification of signals, defined as an increase in the intensity of a signal through networks of intracellular reactions, is considered one of the essential properties in many cell signalling pathways. Despite of the apparent importance of signal amplification, there have been few a...

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Detalles Bibliográficos
Autores principales: Vera, Julio, Bachmann, Julie, Pfeifer, Andrea C, Becker, Verena, Hormiga, Jose A, Darias, Nestor V Torres, Timmer, Jens, Klingmüller, Ursula, Wolkenhauer, Olaf
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2386439/
https://www.ncbi.nlm.nih.gov/pubmed/18439261
http://dx.doi.org/10.1186/1752-0509-2-38