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Overexpression of Scg5 increases enzymatic activity of PCSK2 and is inversely correlated with body weight in congenic mice

BACKGROUND: The identification of novel genes is critical to understanding the molecular basis of body weight. Towards this goal, we have identified secretogranin V (Scg5; also referred to as Sgne1), as a candidate gene for growth traits. RESULTS: Through a combination of DNA microarray analysis and...

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Detalles Bibliográficos
Autores principales: Farber, Charles R, Chitwood, James, Lee, Sang-Nam, Verdugo, Ricardo A, Islas-Trejo, Alma, Rincon, Gonzalo, Lindberg, Iris, Medrano, Juan F
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2386500/
https://www.ncbi.nlm.nih.gov/pubmed/18439298
http://dx.doi.org/10.1186/1471-2156-9-34