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Integrative Survival Response Evoked by Heme Oxygenase-1 and Heme Metabolites
Heme oxygenase (HO) catalyzes the rate-limiting step in heme degradation to produce carbon monoxide (CO), iron, and biliverdin. Biliverdin is subsequently converted to bilirubin by its reductase, and iron is recycled for heme synthesis. The inducible HO isoform, HO-1, is involved in the protection o...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
the Society for Free Radical Research Japan
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2386522/ https://www.ncbi.nlm.nih.gov/pubmed/18545641 http://dx.doi.org/10.3164/jcbn.2008029 |