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Iron(III)-Salophene: An Organometallic Compound with Selective Cytotoxic and Anti-Proliferative Properties in Platinum-Resistant Ovarian Cancer Cells

BACKGROUND: In this pioneer study to the biological activity of organometallic compound Iron(III)-salophene (Fe-SP) the specific effects of Fe-SP on viability, morphology, proliferation, and cell-cycle progression on platinum-resistant ovarian cancer cell lines were investigated. METHODOLOGY/PRINCIP...

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Detalles Bibliográficos
Autores principales: Lange, Thilo S., Kim, Kyu Kwang, Singh, Rakesh K., Strongin, Robert M., McCourt, Carolyn K., Brard, Laurent
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2386551/
https://www.ncbi.nlm.nih.gov/pubmed/18509533
http://dx.doi.org/10.1371/journal.pone.0002303