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Molecular characterization of senescence marker protein-30 gene promoter: Identification of repressor elements and functional nuclear factor binding sites

BACKGROUND: Senescence marker protein-30 (SMP30), whose expression declines during aging in rat liver, has been proposed as an important aging marker. Besides apoptosis, SMP30 also protects cells against various other injuries by enhancement of membrane calcium-pump activity. The mechanism of this d...

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Detalles Bibliográficos
Autores principales: Rath, Bandita, Pandey, Ravi S, Debata, Priya R, Maruyama, Naoki, Supakar, Prakash C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2386801/
https://www.ncbi.nlm.nih.gov/pubmed/18442420
http://dx.doi.org/10.1186/1471-2199-9-43