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Differential protein expression following low temperature culture of suspension CHO-K1 cells
BACKGROUND: To ensure maximal productivity of recombinant proteins (rP) during production culture it is typical to encourage an initial phase of rapid cell proliferation to achieve high biomass followed by a stationary phase where cellular energies are directed towards production of rP. During many...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2386802/ https://www.ncbi.nlm.nih.gov/pubmed/18430238 http://dx.doi.org/10.1186/1472-6750-8-42 |