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A Novel Tumor-Promoting Function Residing in the 5′ Non-coding Region of vascular endothelial growth factor mRNA

BACKGROUND: Vascular endothelial growth factor-A (VEGF) is one of the key regulators of tumor development, hence it is considered to be an important therapeutic target for cancer treatment. However, clinical trials have suggested that anti-VEGF monotherapy was less effective than standard chemothera...

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Detalles Bibliográficos
Autores principales: Masuda, Kiyoshi, Teshima-Kondo, Shigetada, Mukaijo, Mina, Yamagishi, Naoko, Nishikawa, Yoshiko, Nishida, Kensei, Kawai, Tomoko, Rokutan, Kazuhito
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2386836/
https://www.ncbi.nlm.nih.gov/pubmed/18494554
http://dx.doi.org/10.1371/journal.pmed.0050094