In Vitro Evaluation of a Stable Monomeric Gold(II) Complex with Hematoporphyrin IX: Cytotoxicity against Tumor and Kidney Cells, Cellular Accumulation, and Induction of Apoptosis

The antineoplastic potential of a stable monomeric Au(II) complex with hematoporphyrin IX (Hp), namely [Au(II)Hp(−2H).(H(2)O)(2)], was investigated in a panel of tumor cell lines. The complex exhibits strong cytotoxicity, whereby the leukaemia- and lymphoma-derived cell lines are more sensitive, wit...

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Detalles Bibliográficos
Autores principales: Momekov, Georgi, Ferdinandov, Dilyan, Konstantinov, Spiro, Arpadjan, Sonja, Tsekova, Daniela, Gencheva, Galina, Bontchev, Panayot R., Karaivanova, Margarita
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2386889/
https://www.ncbi.nlm.nih.gov/pubmed/18497870
http://dx.doi.org/10.1155/2008/367471

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2386889/
https://www.ncbi.nlm.nih.gov/pubmed/18497870
http://dx.doi.org/10.1155/2008/367471

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