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A Low Dose of Dietary Resveratrol Partially Mimics Caloric Restriction and Retards Aging Parameters in Mice

Resveratrol in high doses has been shown to extend lifespan in some studies in invertebrates and to prevent early mortality in mice fed a high-fat diet. We fed mice from middle age (14-months) to old age (30-months) either a control diet, a low dose of resveratrol (4.9 mg kg(−1) day(−1)), or a calor...

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Detalles Bibliográficos
Autores principales: Barger, Jamie L., Kayo, Tsuyoshi, Vann, James M., Arias, Edward B., Wang, Jelai, Hacker, Timothy A., Wang, Ying, Raederstorff, Daniel, Morrow, Jason D., Leeuwenburgh, Christiaan, Allison, David B., Saupe, Kurt W., Cartee, Gregory D., Weindruch, Richard, Prolla, Tomas A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2386967/
https://www.ncbi.nlm.nih.gov/pubmed/18523577
http://dx.doi.org/10.1371/journal.pone.0002264