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MMP19 Is Essential for T Cell Development and T Cell-Mediated Cutaneous Immune Responses

Matrix metalloproteinase-19 (MMP19) affects cell proliferation, adhesion, and migration in vitro but its physiological role in vivo is poorly understood. To determine the function of MMP19, we generated mice deficient for MMP19 by disrupting the catalytic domain of mmp19 gene. Although MMP19-deficie...

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Detalles Bibliográficos
Autores principales: Beck, Inken M., Rückert, René, Brandt, Katja, Mueller, Markus S., Sadowski, Thorsten, Brauer, Rena, Schirmacher, Peter, Mentlein, Rolf, Sedlacek, Radislav
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2386969/
https://www.ncbi.nlm.nih.gov/pubmed/18523579
http://dx.doi.org/10.1371/journal.pone.0002343