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Liposomal Co-Entrapment of CD40mAb Induces Enhanced IgG Responses against Bacterial Polysaccharide and Protein

BACKGROUND: Antibody against CD40 is effective in enhancing immune responses to vaccines when chemically conjugated to the vaccine antigen. Unfortunately the requirement for chemical conjugation presents some difficulties in vaccine production and quality control which are compounded when multivalen...

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Detalles Bibliográficos
Autores principales: Hatzifoti, Caterina, Bacon, Andrew, Marriott, Helen, Laing, Peter, Heath, Andrew W.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2387064/
https://www.ncbi.nlm.nih.gov/pubmed/18523585
http://dx.doi.org/10.1371/journal.pone.0002368